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Considering this is a newer version of the original Pokemon game 'Pokemon Red' for the gameboy color I will have to comment on that game also and I will compare and contrast both games too. The graphics within this game are really spectacular, I can clearly see the creators of this game really put in a great amount of time and effort into making this game's graphics superb, they obviously took a look back at the previous version of this game, the original Pokemon Red which was specifically made for the Gameboy Color. The creators enhanced the colouring, the sprites, the scenery and the overall presentation of the game greatly which deserves a huge amount credit, that they do deserve. I thought the creators did excellent job in making the graphics of this game amazing. Lets start with the character sprites. I fell in love with the character sprites immediately, it was almost instantaneous as I could see great improvements made in the use of colouring in this version than to the previous Pokemon Red. ![]() File Name: Pokemon Fire Red Rom: Platform: Game Boy Advance: Released: Jan 29, 2004 (JP) / Sep 09, 2004 (US) / Oct, 2004 (EU) Publisher: Nintendo / The Pokemon Company: Developer: Game Freak: Genre: Roleplaying Game: Players. The characters are extremely attractive in the sense that they particularly relate to the Pokemon anime series. The hat/cap that the main character (you) is attired with in the game is really awesome, it is the original hat/cap that Ash Ketchum (the main character in the anime series) wears which I really like. The great use of fiery & ruby reds used on the hat/cap were extremely vivid and precise, the vivid reds of the hat/cap obviously tying in with the title of the game Pokemon 'Fire Red' which is extremely effective and relates to the game perfectly. The colour used in the particular clothing that 'Ash' is acquired with is also very eye- pleasing, there was also a great use of vivid reds and dazzling whites used in the making of these clothes, although not much detail was put into clothing of this character it was still particularly brilliant because as I said before, it ties in with the anime series which is ever so effective. Now for the rival character introduced in the game (Gary), this character'a visual appearance in the game isn't as pleasing as Ash's. The shading of the colour black wasn't used effectively on Gary's torso, when I say torso I refer to his upper clothing. In the anime series Gary's top/t- shirt is very attractive in that there is a great use of blacks and grays, we didn't get that with the game. The blacks used on Gary's torso were faded and very dim and discoloured which didn't attract me to the game at all, a little bit more effort into Gary's clothing would have made a great impact on my thoughts and opinions of the graphics used on this character's clothing. However, having said that, there was tremendous efforts used in the characters facial expression and hair, there was great uses of browns and whites. The brown colouring for his hair were fantastic, there were good visual aids used in this particular area of the characters sprite, even on his face too, the pale- ish white colours were used effectively and they didn't go too heavily on the shading also which is very good and great to see. All in all, the character sprites in this game were generally impressive and should be given credit. ![]() The Scenery - Oh my word, the scenery in this game is extremely, extravagantly epic in my opinion. Lets start with the trees, caves, routes, pathways, all of the natural substances in the game. The trees and grass in this game were utterly amazing and that's an understatement. There were many shadings of green used in this particular aspect of the game, there were light, faded greens which may have signified the light shining upon them which is extremely effective as it relates to everyday life, plants do react to sunlight in that way. As we began to look at the outer parts of the trees the colours got darker and darker as they sprung out from the core of the tree, not forgetting that the trees are tightly spaced together, this ties in with the darker colours that were used in the making of the trees as we all know as trees get closer parts of it shuffle behind another tree, this prevents light reaching that part of the tree and thus the greens get darker. Very powerful and we can relate to this, this is what I want to see in a game's graphics - attention to detail. This also applies to the grass. The colours of brown used in the making of the outer parts of the caves were also very precise and clear as there were many different shadings used. There were also cracks in the caves which obviously shows the creators really went all out and there was evidence that attention to detail was key here and they pulled it off fantastically. The interiors of the caves were also amazing, the lighting was reduced and it really made me feel as if I was in a cave myself, this is very effective and again ties in with real life. The flooring of the interiors of the caves were also worked on very well, there were great shadings of browns/oranges/greys and blacks, as you can see many colours were introduced and were all mixed sparingly, meaning it wasn't patchy or uneven. The towns - the towns in this game were specifically tremendous, there was so much attention to detail. I thought 9. 0% of the towns in the game were extremely well built and structured however, I didn't particularly like Pallet Town, the first ever town you visit as it's Ash's hometown of course. The colouring used in the house and scenery of this town were really inadequate, all features of the town appeared to be really faded and I refer to the colours when I say that. They made me feel like I was in the 1. And, for the sheer size of the town, it's very small therefore time could have been spent on improving the visuality of the town, the appearance. As I said before, this is the first town a player of this game will see therefore it must be very pleasing and attractive as it will appeal to the player and make them want to see more of the amazing graphics in store for them in the game. Having said that, many towns were extremely detailed and a lot of effort went into them, especially Saffron City, The use of gold in this town was very attractive. The town was itself was spectacular, the cobbled paths were really attractive, great use of grays/whites and blacks were used. The buildings locations in the town weren't too great in my opinion, some necessary buildings were hard to locate at times. But seriously, this was one of the best towns in the game. Sounds 1. 0/1. 0In my precious review of the game Pokemon Shiny Gold I referred to this game many times about the sound, so this will very similar to that particular section of that review. The sounds in this game were very similar to that of the sounds in Pokemon Red. I'm very pleased with that actually because the sounds in that game were amazing, it brought back special memories. The classic sound that plays when you catch your first Pokemon, even though it plays every time you catch a Pokemon it's still pretty awesome and really nice to listen to. It makes you feel that you completed a goal and to be proud of yourself. I also really enjoyed the creepy tunes of the basements in the game it makes you feel that your on a mission and you can't be seen. It really pulls on your senses, you're always alert and ready for battle in the basements because of the music. The Pokemon battle music is also very awesome to listen to, it's a really fast tune that gets your blood pumping and makes you really competitive and therefore you really want to win, and probably will do so. The music also has great vibes to it. I really enjoyed listening to music in Saffron City, the music in that city is very calm and relaxing it really soothes you after all the battles in the routes before that town. The music in Celadon's Game Corner is specifically amazing too, it is a very happy and playful tune and was a perfect choice for that particular venue. Also, the Pokemon league music was extremely fierce! The tunes were very fast and upbeat and filled you with determination and at times ruthlessness, it also made you believe that you could conquer the league and that's all I needed to succeed. Addictiveness 9/1. This game is very, very addictive, oh my word is it addictive. When I was a kid I would play this game until the cows came home and I still do play it all the time, it's an amazing game and it really created my childhood! The more I played this game the more I fell in complete love with it. There were so many different things you could do, there were no end to the possibilities! The KANTO region is by far the best region is whole world of Pokémon, the Pokemon within this particular region are incredible! In this game you have the three starters you could ever ask for in Pokémon, in my opinion - Charmander the fiery devil, Squirtle the blue beast, and Bulbasaur the lazy lump! These Pokémon made me an addict to the game, they are so awesome and dominant. Also, the legendary Pokémon were extremely extravagant, in my opinion the best legendary Pokémon in the history of Pokémon! You have Lugia, HO- OH, Entei/Raikou/Suicine, Mew Two, Deoxys and many more, that is what drew me into the game and made me want to play it even more, the variety of legendaries available. There was no end to the Pokémon battles, every corner you turned there was a trainer that you had to conquer and defeat, this made the game extremely addictive and made it that there was always something to do even if it was just battling! As you may have noticed from previous reviews, I love battling, because it provides me with excitement and adrenalin, and of course thrill which I really love in a game. The Pokemon battles in this game were actually very challenging and sometimes it was nearly impossible to beat the rival trainer, but this is a good thing because the more challenging a game is, the more fun you get out of it, and I also love difficult battles too! 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Surgical Management of Penile and Preputial Neoplasms in Equine with Special Reference to Partial Phallectomy. Surgery, Anaesthesiology and Radiology Department, Faculty of Veterinary Medicine, Mansoura University, Mansoura, 3. Dakahlia, Egypt. 2King Fahd Medical Research Center, King Abdulaziz University, 2. Jeddah, Saudi Arabia. Biology Science Department, King Abdulaziz University, 2. Jeddah, Saudi Arabia. Copyright В© 2. 01. Awad Rizk et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Penile and preputial neoplasia in horses occurs infrequently and represents diagnostic and therapeutic challenges. The present study was carried out on a total number of 2. Diagnosis of neoplasms was based up on history of the case, clinical examination as well as histopathological evaluation. Animals with penile and preputial neoplasms were underwent local excision and partial phallectomy with a slightly modified version of the techniques described by William’s. The diagnosed neoplasms were penile and preputial squamous cell carcinomas (SCCs; ); sarcoid (); a- fibrosarcoma; and a melanoma. Local excision was curative in all cases except 5 stallions with SCCs. These stallions had extensive damage of the glans penis, free part of the penis and the inner lamina of the internal fold of the prepuce, and they underwent a partial phallectomy with successful outcome. Follow- up information was obtained by visit and telephone inquiries. In conclusion, penile and preputial neoplasms are commonly encountered in elderly male horses and SCCs are the most common type affecting male external genitalia. EQUITANA Melbourne is pleased to present an exciting and innovative Education Program in 2016. Watch as local and international experts present displays, seminars, interactive question and answer sessions and training. Partial phallectomy is effective for management of equine neoplasia if they are confined to the glans and body of the penis and there is no proximal spread or involvement to regional lymph nodes. Introduction. Penile and preputial neoplasia is more prevalent in equine than in other domestic animals; they occupied about 6 and 1. Squamous cell carcinomas (SCCs) are the most common form of penile and preputial neoplasia [3–5]; however sarcoids, squamous cell papillomas, melanomas, fibromas, fibrosarcoma, and haemangiomas have been reported [3, 4, 6, 7]. Penile and/or preputial neoplasia can cause discomfort and in advanced cases can result in systemic disease [8–1. SCCs are the commonest neoplasm involving the penis, prepuce, or both [6]. It represents 2. 0% of all equine tumours, making it the second most common tumour in horses. Using other people’s research or ideas without giving them due credit is plagiarism. Since BibMe™ makes it easy to create citations, build bibliographies and acknowledge other people’s work, there is no excuse to. Policy. The Australian Veterinary Association (AVA) supports practices that: ensure the safety and welfare of all animals under veterinary care; provide a safe and healthy working environment for owners, veterinarians and. A gelding is a castrated horse or other equine, such as a donkey or a mule. Castration, as well as the elimination of hormonally driven behavior associated with a stallion, allows a male horse to be calmer and better-behaved. It is a malignant tumour mainly affecting adult horses [5, 6, 1. SCCs of the penis and prepuce are locally invasive but usually show only low- grade malignancy [2]. These tumours may metastasize to regional lymph nodes if not treated aggressively. Recurrence after surgical excision can be expected in 1. Long- standing SCCs can interfere with coitus or normal protrusion and retraction of the penis and most penile SCCs involve the glans penis (5. Fibrosarcoma is a malignant tumor derived from fibrous connective tissue and characterized by immature proliferating fibroblasts or undifferentiated anaplastic spindle cells. Veterinary Medicine Websites Introduction. To find veterinary medicine related websites, choose from the topics listed below. Topics. It is unusual mesenchymal tumor in male genitalia of man [1. Equine sarcoid is a locally aggressive, fibroblastic skin tumour, which can appear as a flat or cauliflower- like growth either singularly or multiple growths, usually in young horses [1. Sarcoids have been clinically categorized into several groups including verrucous, fibroblastic, mixed verrucous and fibroblastic, occult, nodular, and malevolent. Some of these subtypes can occur with any frequency on the equine penis and prepuce [1. Melanocytic tumours have been reported to affect all parts of the penis and prepuce other than the glans [4, 9, 1. Malignant melanomas were seen predominantly in older nongrey horses and melanocytic nevi occurred in young horses of all coat colours [7, 1. Recently, a standard protocol has been proposed to aid treatment selection of horses with penile and preputial tumours. Treatments were ranged from minimally invasive interventions (e. Surgical modalities include local excision, segmental posthioplasty, partial phallectomy, partial phallectomy and sheath ablation, and en bloc penile and preputial resection with penile retroversion [2, 1. Local excision is indicated to remove small, solitary tumours, such as focal SCCs, squamous papilloma, and sarcoid, where there is no evidence of metastasis to regional lymph nodes or invasion to deeper structures. Local excision is usually curative for horses with melanocytic nevi and solitary dermal melanomas [2. Partial phallectomy, such as Scott’s, Williams’, or Vinsot’s techniques, is indicated only if the distal portion of the penis (the glans and shaft of the penis) is involved and there is no proximal spread and without involvement of the prepuce and regional lymph nodes [4, 5]. Involvement of prepuce, urethra, and cavernous tissue are indications for performing more radical surgery [2. The present study aimed to examine various types of penile and preputial neoplasia in horses and donkeys in our region and investigate the results of the surgical intervention using a modified version of Williams’s technique for partial phallectomy. Materials and Methods. The present study was carried out on a total number of 2. Tables 1 and 2). These animals were admitted to Mansoura Veterinary Teaching Hospital of the Faculty of Veterinary Medicine, Mansoura University, Mansoura, Egypt. The age was ranged from 4 to 1. Table 2). Diagnosis was based on history of the case and clinical examination of each mass including location, size, age as well as histopathological examinations. Table 1: Showing type, breed, number, and percentage of penile and preputial neoplasms in stallion and Jack donkey . Table 2: Showing a patient data including animal species, age, tumour types, treatment, recurrence, followup, second treatment, second recurrence, and followup of penile and preputial neoplasms in stallion and Jack donkey . Clinical Examination. Clinical examination was performed of the penis and prepuce. Examination of the penis itself and the internal fold of the prepuce required sedation with intravenous detomidine 1% (Domosedan, Pfizer) in a dose of 0. Superficial inguinal lymph nodes were examined. Surgical Intervention. Each animal was held off feed for 1. IU/kg, IM) and phenylbutazone (2. IV; Phenyloject, Adwia, Egypt) prior to general anesthesia. Anesthesia was induced and maintained by infusion of a freshly prepared mixture of 3 mg medetomidine (3 μg/m. L), 4. 0 mg midazolam (0. L) and 2 gm ketamine (2 mg/m. L) dissolved in 1 liter of dextrose 5% in animals either underwent local excision or partial phallectomy. Local Excision The observed lesions were surgically resected through a wide surgical excision in the surrounding healthy tissues by 1- 2 cm. Two Penrose drains were placed, exiting the incision laterally. Primary closure of the incision was accomplished using a series of interrupted vertical mattress sutures using prolene (Braun- Aesculap, Tuttlingen, Germany) no. Partial Phallectomy with a Modified Williams’s [2. Technique. This modified technique was performed in five stallions diagnosed SCCs at the glans penis (3 horses), free part of the penis, and the inner lamina of the internal fold of the prepuce (2 horses). Horses were positioned in dorsal recumbency. A catheter was placed in the urethra and advanced into the bladder as a guide to aid in dissection of the urethra and to evacuate urine at the end of the procedure. Soft- roll gauze was used to tie the free part of the penis to an overhead support to facilitate aseptic preparation. The glans and proximal free part of the penis were covered in a sterile bandage. A latex tourniquet was placed proximal to preputial ring. The penis, prepuce, and the surrounding ventral abdomen were aseptically prepared and the area was draped. A triangular incision (base 3 cms and sides 5 cms) was made through the penile skin on the ventral midline of the penis, with the apex pointing in a proximal direction. The base of the triangle was proximal to corona glandis and it was the site of penile transection. This triangle was bluntly dissected. A longitudinal incision was made into the urethra from the apex to the base of the triangle. The incised edges of the urethral mucosa were opposed to the epithelial edges of the sides of the triangle with simple continuous sutures (Figure 1(b)) using polydiaxanone no. PDS, Braun- Aesculap, Tuttlingen, Germany). The base of the triangle was left unsutured. The urethral catheter was removed, and the penis was obliquely transected at the base of the triangle in a craniodorsal direction (Figure 1(c)). The tunica albuginea of the dorsum of the corpus cavernosum penis was sutured to the tunical albuginea of the urethral groove with equidistant simple interrupted sutures using PDS no 0. The urethral mucosa was sutured to the penile epithelium with simple interrupted sutures using the same suture material. Open covered castration was performed in these 5 stallions at the same time of surgery. Figure 1: Cauliflower- like SCC at the glans penis of horse (white arrow). The incised edges of the urethral mucosa were opposed to the epithelial edges of the sides of the triangle with simple continuous suture (white arrow; b). Stroma of partial phallectomy (c). Histological structure of SCCs showing small aggregates, irregular islands, and nests of neoplastic keratinocytes (black arrow) that proliferate downward from the epidermis and invade the subepithelial stroma of the dermis (H & E ×4. Postoperative Care. The preoperative antibiotic and anti- inflammatory were continued for 5 days. A prophylactic dose of antitetanic serum was injected. Wound dressing using povidone iodine was performed twice daily. Animals were confined to a stall without exercise for 5 days after surgery. Histopathological Examination. Rego Regulator | e. Bay. Unique bonnet vent profile minimizes vent freeze over when properly installed. Low Pressure Second Stage Regulator designed to reduce first stage pressure of 5 to 2. PSIG down to burner pressure, norm.. 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